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Introduction
ABBA Lab
Contact us
Member
Professor
Student
Alumni
Research
3D Printing for hard tissue engineering
3D Printing for soft tissue engineering
Fabrication of porous scaffolds
Advanced surface modification
Publication
Journal
Patent
Board
News
Gallery
Lecture
ABBA Lab
Advanced Biomaterials for Biomedical Applications Lab
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Introduction
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> > > This study examined the utility of a combination of the thermoplastic green machining (TGM) and micro-arc oxidation (MAO) for the production of porous Ti scaffolds with 3-dimensional (3-D) periodic macrochannels coated with a microporous TiO2 layer, which would provide high mechanical properties and excellent biocompatibility simultaneously. The TGM technique allowed for the creation of tightly controlled 3-D periodic macrochannels with a diameter of ∼828–837 μm by machining a thermoplastic compound consisting of 70 vol% titanium hydride (TiH2) powder and 30 vol% thermoplastic binders, followed by heat-treatment in a vacuum. The overall porosity and mechanical properties of the porous Ti scaffolds were controlled by creating various periodic arrays of 6 × 6, 7 × 7, or 8 × 8 macrochannels in each face of a cube. The compressive strength and modulus was decreased from 358 ± 7 to 100 ± 8 MPa and from 5.2 ± 0.66 to 3.5 ± 0.32 GPa, respectively, with increasing porosity from 48 vol% to 64 vol%. The biocompatibility and bioactivity, which was assessed by in vitro cellular assays, were improved remarkably by creating a microporous TiO2 coating layer using the MAO treatment. > >
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